NovoPro
Cart 2
  • Mouse Fas/Apt1/Tnfrsf6 (His tag) recombinant protein

Mouse Fas/Apt1/Tnfrsf6 (His tag) recombinant protein

Cat.#: 519905

Special Price 265.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Mouse Fas/Apt1/Tnfrsf6 (His tag) recombinant protein
  • Documents
  • Description
    Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected in various tissues including thymus, liver, lung, heart, and adult ovary. As a receptor for TNFSF6/FASLG, The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
  • Protein name
    Fas (TNF receptor superfamily member 6)(Fas)
  • Protein short names
    Apt1; Tnfrsf6
  • Uniprot ID
    P25446
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Fas/Apt1/Tnfrsf6 Gln22-Arg169 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Fas/Apt1/Tnfrsf6 (His tag) recombinant protein

    Mouse Fas/Apt1/Tnfrsf6 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"