Human FAS/APT1/FAS1/TNFRSF6 (Fc tag) recombinant protein

Cat.#: 518447

Size:

Special Price 438.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human FAS/APT1/FAS1/TNFRSF6 (Fc tag) recombinant protein
  • Documents
  • Description
    FAS(TNFRSF6) is a receptor and contains three TNFR-Cys repeats and one death domain. It has been shown that FAS is involved in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. FADD (adapter molecule) recruits caspase-8 to the activated receptor, the resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis. FAS-mediated apoptosis may play a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
  • Protein name
    Fas cell surface death receptor(FAS)
  • Protein short names
    APT1; FAS1; TNFRSF6
  • Uniprot ID
    P25445
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human FAS/APT1/FAS1/TNFRSF6 Gln26-Asn173 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human FAS/APT1/FAS1/TNFRSF6 (Fc tag) recombinant protein

    Human FAS/APT1/FAS1/TNFRSF6 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"