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Neuropeptides

A neuropeptide is an endogenous protein molecule comprised of at least two amino acids, which are chained together by peptide bonds. They are found in large dense-core vesicles on nearly all areas of the neuron, most commonly the axon terminal at the synapse. Approximately 100 different neuropeptides have been identified.

The function of a neuropeptide often determines its classification as a neurotransmitter or hormone, but the terms are frequently intermixed. Generally, neuropeptides exert more prolonged and diverse effects on behavior than neurotransmitters, and act directly at G-coupled protein and metabotropic receptor sites. 

Many populations of neurons have distinctive biochemical phenotypes. For example, in one subpopulation of about 3000 neurons in the arcuate nucleus of the hypothalamus, three anorectic peptides are co-expressed: α-melanocyte-stimulating hormone (α-MSH), galanin-like peptide, and cocaine-and-amphetamine-regulated transcript (CART), and in another subpopulation two orexigenic peptides are co-expressed, neuropeptide Y and agouti-related peptide (AGRP). These are not the only peptides in the arcuate nucleus; β-endorphin, dynorphin, enkephalin, galanin, ghrelin, growth-hormone releasing hormone, neurotensin, neuromedin U, and somatostatin are also expressed in subpopulations of arcuate neurons. These peptides are all released centrally and act on other neurons at specific receptors. The neuropeptide Y neurons also make the classical inhibitory neurotransmitter GABA.

Invertebrates also have many neuropeptides. CCAP has several functions including regulating heart rate, allatostatin and proctolin regulate food intake and growth, bursicon controls tanning of the cuticle and corazonin has a role in cuticle pigmentation and moulting.

Cat#Product NameSizePrice
300038Crayfish RFamide 1 / Neuropeptide DF2 (DRNFLRF-amide), an FMRFamide5 mg62.2
300191H-Gly-Gly-Gly-OH, Neuropeptide-like peptide, NLP-32-35 mg69.0
300284FMRFamide-like neuropeptide, AF15 mg62.2
300308[D-Tyr27,36, D-Thr32]-Neuropeptide Y, human5 mgInquiry
300455A-18-F-NH2; Morphine Modulating Neuropeptide5 mg160.0
300588(Pro34)-Neuropeptide Y (porcine)5 mg414.0
301121Neuropeptide-gamma5 mg241.5
301157Neuropeptide EI-Gly-Arg-Arg-MCH (human, mouse, rat)5 mg502.5
301277Neuropeptide Y (2-36) (porcine)5 mg402.5
301488Pheromonotropin (Pseudaletia separata), Pheromonotropic neuropeptide5 mg207.0
301496Neuropeptide W-23 (rat)5 mg264.5
301525Neuropeptide Y (22-36)5 mg172.5
301696Octa-neuropeptide, Octapeptide OP5 mg92.0
302346Neuropeptide AF (hNPAF), Human /Neuropeptide A-18-F/NPAF5 mg207.0
302418(Tyr(Me)21)-Neuropeptide Y (human, rat)5 mgInquiry
302992Neuropeptide Y-Lys(Biotin), human, rat; NPY-Lys(Biotin), human, rat5 mg328.0
303424Pheromone Biosynthesis Activating Neuropeptide5 mg379.5
303465FMRF-like Neuropeptide; SchistoFLRFamide5 mg115.0
303627Neuropeptide Y (18-36)5 mg218.5
303654LWamide neuropeptide II, He-LWamide II5 mg69.0
303757Neuropeptide W-30 (human)5 mg345.0
303951Galanin (1-13)-Neuropeptide Y (25-36) amide5 mg287.5
303984(Leu31,Pro34)-Neuropeptide Y (human, rat)5 mg414.0
304903Neuropeptide-glutamic acid-isoleucine, Neuropeptide EI (human, mouse, rat)5 mg149.5
305200Neuropeptide K5 mg414.0
305279[D-Trp34]-Neuropeptide Y, human; [D-Trp34]-NPY, human5 mgInquiry
305624[S1]-Mollusca neuropeptide, FMRF-related peptide, SDPFLRF-NH25 mg80.5
305706Neuropeptide Y (free acid) (human, rat)5 mg414.0
305765Neuropeptide S (1-10) (human)5 mg115.0
305879Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human)5 mgInquiry
306202(D-Tyr1,N-Me-Phe3)-Neuropeptide FF5 mgInquiry
306416Neuropeptide GE (Glycine-Glutamic acid)5 mg218.5
306442[D-Arg25]-Neuropeptide Y, human, rat; [D-Arg25]-NPY, human, rat5 mgInquiry
306938Neuropeptide RFRP-25 mg207.0
306981((Cys31,Nva34)-Neuropeptide Y (27-36))25 mgInquiry
307359Neuropeptide VF (56-92) (human), RFRP-15 mg425.5
307563Neuropeptide Y / Melanostatin, frog5 mg320.0
307572Neuropeptide F5 mg346.7
308212Neuropeptide W-30 (rat)5 mg345.0
308648(His32,Leu34)-Neuropeptide Y (32-36)5 mg69.0
308894Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human)5 mgInquiry
309169Neuropeptide 26RFa, Hypothalamic Peptide, frog5 mg231.1
309402Neuropeptide SF (human)5 mg126.5
309441[Thr30]-Neuropeptide Y, human5 mg414.0
309624Neuropeptide Y (13-36) (human, rat)5 mg276.0
310317Neuropeptide VF (124-131) (human)5 mg92.0
310850Tyr-Lys-Gly-(Cyclo(Glu26-Lys29),Pro34)-Neuropeptide Y (25-36)5 mgInquiry
310965Orphan GPCR SP9155 Agonist P518, Neuropeptide 26RFa, Hypothalamic Peptide5 mg299.0
310966Neuropeptide FF (5-8)/Morphine Modulating Peptide, C-Terminal Fragment5 mg69.2
311205(Ala31,Aib32)-Neuropeptide Y (porcine)5 mgInquiry
311531Neuropeptide Y (3-36) (porcine)5 mg391.0
311598Neuropeptide Y5 mg414.0
311735(D-Trp32)-Neuropeptide Y (human, rat)5 mgInquiry
312151Neuropeptide S (human)5 mg230.0
312438Bradykinin-Like Neuropeptide (Aplysia californica)5 mg126.5
312508(Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36)5 mg103.5
312541(D-Tyr27-36,D-Thr32)-Neuropeptide Y (27-36)5 mgInquiry
312998Neuropeptide Y (1-24) amide (human, rat)5 mg276.0
313085[Pro34]-Neuropeptide Y, human, rat; [Pro34]-NPY, human, rat5 mg320.0
313101(Cys2)-Neuropeptide Y (1-4)-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32)5 mgInquiry
313139Biotinyl-(Des-Bromo)-Neuropeptide B (1-23) (human)5 mgInquiry
313177Biotinyl-Neuropeptide W-23 (human)5 mgInquiry
313806H-Gly-Trp-Gly-OH, Neuropeptide-like peptide, NLP-32-95 mg69.0
313810(Leu31,Pro34)-Neuropeptide Y (13-36) (human, rat)5 mg276.0
313828[D-His26]-Neuropeptide Y, human, rat; [D-His26]-NPY, human, rat5 mgInquiry
313977(Des-Bromo)-Neuropeptide B (1-23) (human)5 mg264.5
314349H-Gly-Gly-Gly-Gly-OH, Neuropeptide-like peptide, NLP-32-75 mg69.0
314353(D-Trp32)-Neuropeptide Y (porcine)5 mgInquiry
314362Biotinyl-Neuropeptide Y (human, rat)5 mgInquiry
314363Acetyl-(Leu28-31)-Neuropeptide Y (24-36)5 mgInquiry
314408Neuropeptide Y (3-36) (human, rat)5 mg391.0
314522Neuropeptide FF Morphine Modulating Neuropeptide F-8-F/NPFF5 mg92.0
314580Orphan GPCR SP9155 Agonist P550/Neuropeptide 26RFa/Hypothalamic Peptide5 mg299.0
314639Neuropeptide Y (13-36) (porcine)5 mg213.4
314705DL-2,7-Diaminosuberoyl-((Tyr32,Leu34)-Neuropeptide Y (32-36))25 mgInquiry
314925Neuropeptide Y5 mg414.0
315357Bradykinin-Like Neuropeptide (3-11) (Aplysia californica)5 mg80.0
315381Neuropeptide Y (2-36) (human, rat)5 mg311.2
315535Neuropeptide S (rat)5 mg230.0
316044(Leu31,Pro34)-Neuropeptide Y (porcine)5 mg414.0
318153neuropeptide NAP5 mg71.1