Mouse Ephrin-A5/EFNA5 (His Tag) recombinant protein
Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A5/EFNA5 may function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Ephrin-A5/EFNA5 also serves as a cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
Protein short names
EFL5; EFNA5; EPL7; RAGS; AL-1; LERK-7; EPHRIN-A5; GLC1M; AV158822; LERK7; EFL-5; AF1; EPLG7
Efna5; Epl7; Eplg7; Lerk7
A DNA sequence encoding the mouse EFNA5 isoform long (O08543-1) without the pro peptide (Met 1-Asn 203) was expressed, with a polyhistidine tag at the C-terminus.
The recombinant mouse EFNA5 consists of 194 amino acids and has a predicted molecular mass of 22.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmEFNA5 is approximately 28 kDa due to glycosylation.
> 97 % as determined by SDS-PAGE
Measured by its binding ability in a functional ELISA. Immobilized Mouse EPHA5 at 2 μg/ml (100 μl/well) can bind mouse EFNA4 with a linear ranger of 1.28-32 ng/ml.
Mouse Ephrin-A5 / EFNA5 Protein (His Tag) SDS-PAGE
Related Products / Services
- Recombinant Proteins
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- Human Ephrin-A5/EFNA5 (His Tag) recombinant protein$70.1
- Rhesus Ephrin-A5/EFNA5 (His Tag) recombinant protein$166.9
- Mouse Ephrin-A5/EFNA5 (Fc Tag) recombinant protein$130.6
- Rat Ephrin-A5/EFNA5 (Fc Tag) recombinant protein$191.1
- Rhesus Ephrin-A5/EFNA5 (Fc Tag) recombinant protein$166.9
- Rat Ephrin-A5/EFNA5 (His Tag) recombinant protein$215.3
- Human EFNA5/EPLG7/LERK7 (Fc tag) recombinant protein$101.2
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