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Product Name
Human CCL2/MCP-1 (His Tag) recombinant protein
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Description
Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
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Protein name
C-C motif chemokine 2
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Protein short names
SMALL INDUCIBLE CYTOKINE A2 (MONOCYTE CHEMOTACTIC PROTEIN 1; CHEMOKINE (C-C MOTIF) LIGAND 2; MEMBER 2; RP23-350G1.3; MONOCYTE CHEMOATTRACTANT PROTEIN 1; HSMCR30; CCL2; SCYA2; SIGJE; AI323594; HC11; MCAF; JE; MCP1; MONOCYTE SECRETORY PROTEIN JE; MONOCYTE CHEMOTACTIC PROTEIN 1; MCP-1; SMALL-INDUCIBLE CYTOKINE A2; HOMOLOGOUS TO MOUSE SIG-JE); PLATELET-DERIVED GROWTH FACTOR-INDUCIBLE PROTEIN JE; SMC-CF; C-C MOTIF CHEMOKINE 2; MONOCYTE CHEMOTACTIC AND ACTIVATING FACTOR; GDCF-2; SMALL INDUCIBLE CYTOKINE SUBFAMILY A (CYS-CYS); SMALL INDUCIBLE CYTOKINE A2
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Uniprot ID
P13500
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Gene Name
CCL2; MCP1; SCYA2
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Source/Expression Host
Yeast
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Expression Plasmid/cDNA
A DNA sequence encoding the human CCL2 (NP_002973.1) (Gln24-Thr99) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CCL2 consists 86 amino acids and predicts a molecular mass of 10.1 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Human CCL2 / MCP-1 / MCP1 Protein (His Tag) SDS-PAGE
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