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  • Human IL-17A & IL-17F (His tag) recombinant protein

Human IL-17A & IL-17F (His tag) recombinant protein

Cat.#: 518899

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Product Information

  • Product Name
    Human IL-17A & IL-17F (His tag) recombinant protein
  • Documents
  • Description
    The IL-17 family include IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25), and IL-17F. The family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. All members of the IL-17 family have a similar protein structure, with four highly conserved cysteine residues critical to their 3-dimensional shape, yet they have no sequence similarity to any other known cytokines. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes.
  • Protein name
    Interleukin-17A & IL-17F Heterodimer
  • Uniprot ID
    Q16552&Q96PD4
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human IL-17A & IL-17F Ile20-Ala155&Arg31-Gln163 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human IL-17A & IL-17F (His tag) recombinant protein

    Human IL-17A & IL-17F (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"