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Human IL17 / IL17a recombinant protein

Cat.#: 503644

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Product Information

  • Product Name
    Human IL17 / IL17a recombinant protein
  • Documents
  • Protein name
    Interleukin-17A
  • Uniprot ID
    Q16552
  • Gene Name
    IL17A; CTLA8; IL17
  • Source/Expression Host
    CHO Stable Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human IL17A(Q16552) (Ile20-Ala155) was expressed with a N-terminal Met.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IL17A consists of 137 amino acids and predicts a molecular mass of 15.7 KDa. It migrates as an approximately 16, 19, and 20 KDa band in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    (16.9+21.7+50.1) % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA. Immobilized human IL17A (cat:503644) at 10 μg/ml (100 μl/well) can bind human IL17Ra (Cat:503306), The EC50 of human IL17Ra (Cat:503306) is 20.0-48.0 ng/ml.
    2. Measured by its ability to induce IL-6 secretion by HFF human foreskin fibroblast cells. The ED50 for this effect is typically 1-4 ng/mL.
  • Validations

    Human IL17 / IL17A Protein SDS-PAGE

    Human IL17 / IL17A Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"