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Product Name
Mouse Nectin2/Mph/Pvr/Pvrl2/Pvs (His tag) recombinant protein
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Description
Nectin-2( CD112) is a member of the nectin family, which contains two Ig-like C2-type domains and one Ig-like V-type domain in the extracellular region. Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Nectin2 is widely expressed in human tissues including brain, spinal cord, spleen, kidney, heart and liver. It can form trans-heterodimers with PVRL3/nectin-3 and interacts with CD226. Mutations of alleles of the murine CD112 gene can result in conditions such as morphologically aberrant spermatozoa. It may function in allergic reactions, and accordingly may used as a novel target for anti-allergic therapy.
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Protein name
nectin cell adhesion molecule 2(Nectin2)
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Protein short names
Mph; Pvr; Pvrl2; Pvs
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Uniprot ID
P32507
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Nectin2/Mph/Pvr/Pvrl2/Pvs Gln32-Gly351 is expressed with a 6His tag at the C-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Nectin2/Mph/Pvr/Pvrl2/Pvs (His tag) recombinant protein
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