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  • Mouse Ccl3/Mip1a/Scya3 (His tag) recombinant protein

Mouse Ccl3/Mip1a/Scya3 (His tag) recombinant protein

Cat.#: 519462

Special Price 156.8 USD

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Product Information

  • Product Name
    Mouse Ccl3/Mip1a/Scya3 (His tag) recombinant protein
  • Documents
  • Description
    C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. Mature mouse CCL3 shares 73%, 91%, and 82% amino acid sequence identity with human, rat, and cotton rat CCL3, respectively. CCL3 exerts its biological functions through interactions with CCR1, CCR3, and CCR5. It is cleared from the extracellular space by internalization via the decoy chemokine receptor D6. CCL3 promotes the chemoattraction, adhesion to activated vascular endothelium, and cellular activation of many hematopoietic cell types including activated T cells, NK cells, neutrophils, monocytes, immature dendritic cells, and eosinophils. CCL3 is also known as stem cell inhibitor (SCI) and can inhibit the proliferation of hematopoietic progenitor cells. CCL3 bioactivity contributes to tumor metastasis and the inflammatory components of viral infection, rheumatoid arthritis, and hepatitis, although it also can suppress the replication of HIV.
  • Protein name
    chemokine (C-C motif) ligand 3(Ccl3)
  • Protein short names
    Mip1a; Scya3
  • Uniprot ID
    P10855
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Ccl3/Mip1a/Scya3 Ala24-Ala92 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Ccl3/Mip1a/Scya3 (His tag) recombinant protein

    Mouse Ccl3/Mip1a/Scya3 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"