-
Product Name
Rat CCL3/Mip1a recombinant protein
- Documents
-
Description
Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.
-
Protein name
C-C motif chemokine 3
-
Protein short names
MACROPHAGE INFLAMMATORY PROTEIN-1ALPHA; TY-5; AI323804; MIP-1 ALPHA; G0S19-1; MIP-1ALPHA; RP23-320E6.7; SMALL INDUCIBLE CYTOKINE A3; TONSILLAR LYMPHOCYTE LD78 ALPHA PROTEIN; PAT 464.1; SIS-ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA; SIS-BETA; MIP1-ALPHA; MIP1A; LD78ALPHA; G0/G1 SWITCH REGULATORY PROTEIN 19-1; MIP-1-ALPHA; C-C MOTIF CHEMOKINE 3; SCYA3; MIP1-(A); L2G25B; MIP1 (A); SMALL INDUCIBLE CYTOKINE A3 (HOMOLOGOUS TO MOUSE MIP-1A); HEPARIN-BINDING CHEMOTAXIS PROTEIN
-
Uniprot ID
P50229
-
Gene Name
Ccl3; Mip1a; Scya3
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the rat CCL3 (P50229) (Ala24-Ala92) was expressed and purified with an initial Met.
-
Protein Species
Rat
-
Molecular weight
The recombinant rat CCL3 consists of 70 amino acids and has a predicted molecular mass of 7.8 kDa. The apparent molecular mass of the recombinant protein is approximately 14 kDa in SDS-PAGE under reducing conditions.
-
Purity
> 95 % as determined by SDS-PAGE
-
Validations
Rat CCL3 / Mip1a Protein SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"