LIN28 antibody

Cat.#: 107377

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Product Information

  • Product Name
    LIN28 antibody
  • Documents
  • Description
    LIN28 Mouse Monoclonal antibody. Positive WB detected in NCCIT cell. Observed molecular weight by Western-blot: 28 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    CSDD1 antibody; FLJ12457 antibody; LIN 28 antibody; lin 28 homolog (C. elegans) antibody; Lin 28A antibody; LIN28 antibody; Lin28A antibody; Protein lin 28 homolog A antibody; ZCCHC1 antibody
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was obtained by immunization of LIN28 recombinant protein (Accession Number: NM_024674). Purification method: Protein G purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

  • Validations

    NCCIT cell were subjected to SDS PAGE followed by western blot with (LIN28 Antibody) at dilution of 1:1000

    NCCIT cell were subjected to SDS PAGE followed by western blot with (LIN28 Antibody) at dilution of 1:1000

  • Background
    LIN28 is one of the four key human factors (ocT4, SOX2, NANOG and LIN28) used to reprogram human fibroblasts to an embryonic stem (ES) cell-like state known as the induced pluripotent stem (Ips) cell. Lin28 is a marker of undifferentiated human embryonic stem cells and a cytoplasmic Mrna-binding protein that binds to and enhances the translation of the IGF2 Mrna. LIN28 has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"