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IL33 antibody

Cat.#: 111738

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Product Information

  • Product Name
    IL33 antibody
  • Documents
  • Description
    IL33 Rabbit Polyclonal antibody. Positive IHC detected in human tonsillitis tissue. Positive WB detected in Transfected HEK-293 cells, HeLa cells, Recombinant protein.
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    C9orf26 antibody; DKFZp586H0523 antibody; DVS27 antibody; IL 1F11 antibody; IL 33 antibody; IL1F11 antibody; IL33 antibody; Interleukin 1 family member 11 antibody; interleukin 33 antibody; NF HEV antibody; NFEHEV antibody; NFHEV antibody; RP11 575C20.2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of IL33 recombinant protein (Accession Number: NM_001314045). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:111738(IL33 Antibody) at dilution of 1:700

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:111738(IL33 Antibody) at dilution of 1:700

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:111738(IL33 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:111738(IL33 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:111738(IL33 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:111738(IL33 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    IL-33 is an IL-1 family cytokine and nuclear alarmin, is constitutively expressed in epithelial barrier tissues and human blood vessels. IL-33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. It also acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury.
  • References
    • Li S, Li X, Wang Y, Yang J, Chen Z, Shan S. Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection. BMC microbiology. 14:27. 2014.
    • Li P, Ma H, Han D, Mou K. Interleukin-33 affects cytokine production by keratinocytes in vitiligo. Clinical and experimental dermatology. 40(2):163-70. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"