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  • Human SMAD1/BSP1/MADH1/MADR1 (GST tag) recombinant protein

Human SMAD1/BSP1/MADH1/MADR1 (GST tag) recombinant protein

Cat.#: 518530

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Product Information

  • Product Name
    Human SMAD1/BSP1/MADH1/MADR1 (GST tag) recombinant protein
  • Documents
  • Description
    SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcriptional modulator SMAD 1 is activated by bone morphogenetic proteins type 1 receptor kinase. Defects in SMAD1 may cause primary pulmonary hypertension (PPH1), characterized by plexiform lesions of proliferating endothelial cells in pulmonary arterioles. The lesions lead to elevated pulmonary arterial pression, right ventricular failure and death.
  • Protein name
    SMAD family member 1(SMAD1)
  • Protein short names
    BSP1; MADH1; MADR1
  • Uniprot ID
    Q15797
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human SMAD1/BSP1/MADH1/MADR1 Met1-Ser465 is expressed with a GST tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human SMAD1/BSP1/MADH1/MADR1 (GST tag) recombinant protein

    Human SMAD1/BSP1/MADH1/MADR1 (GST tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"