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Product Name
Human ESR2/ESTRB/NR3A2 (His tag) recombinant protein
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Description
Estrogen Receptor Beta (ESR2) is a nuclear protein that belongs to the nuclear hormone receptor family of NR3 subfamily. It contains one nuclear receptor DNA-binding domain and is expressed in many tissues at a lower level. ESR2 is a nuclear hormone receptor. It binds estrogens with an affinity similar to that of ESR1 and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
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Protein name
estrogen receptor 2(ESR2)
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Protein short names
ESTRB; NR3A2
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Uniprot ID
Q92731-3
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ESR2/ESTRB/NR3A2 Met1-Ala323 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ESR2/ESTRB/NR3A2 (His tag) recombinant protein
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