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Product Name
Human CD300A/CMRF35H/IGSF12/HSPC083 (His tag) recombinant protein
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Description
CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain, a 21 amino acid transmembrane segment, and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
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Protein name
CD300a molecule(CD300A)
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Protein short names
CMRF35H; IGSF12; HSPC083
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Uniprot ID
Q9UGN4
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CD300A/CMRF35H/IGSF12/HSPC083 Leu18-Gln178 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CD300A/CMRF35H/IGSF12/HSPC083 (His tag) recombinant protein
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