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Product Name
Human CD300A/CMRF35H/IGSF12/HSPC083 (Fc & His tag) recombinant protein
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Description
CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.
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Protein name
CD300a molecule(CD300A)
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Protein short names
CMRF35H; IGSF12; HSPC083
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Uniprot ID
Q9UGN4
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CD300A/CMRF35H/IGSF12/HSPC083 Leu18-Gln178 is expressed with a Fc, 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CD300A/CMRF35H/IGSF12/HSPC083 (Fc & His tag) recombinant protein
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