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Product Name
Human VDR-NR111 (His Tag) recombinant protein
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Description
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
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Protein name
Vitamin D3 receptor
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Protein short names
PPP1R163; NR1I1; VITAMIN D3 RECEPTOR; NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 1; NR111; VITAMIN D NUCLEAR RECEPTOR VARIANT 1; 25-DIHYDROXYVITAMIN D3 RECEPTOR
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Uniprot ID
P11473
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Gene Name
VDR; NR1I1
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human VDR (P11473) (Met 1-Ser 427) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human VDR consists of 437 amino acids and migrates as an approximately 50 KDa band in SDS-PAGE in SDS-PAGE under reducing conditions as predicted.
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Purity
> 88 % as determined by SDS-PAGE
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Validations
Human VDR / NR1I1 Protein (His Tag) SDS-PAGE
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