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Mouse Renin (His Tag) recombinant protein

Cat.#: 502823

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Special Price 532.2 USD

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Product Information

  • Product Name
    Mouse Renin (His Tag) recombinant protein
  • Documents
  • Description
    Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
  • Protein name
    Renin-1
  • Protein short names
    REN1D; REN-A; RN-1; FLJ10761; REN; HNFJ2; D19352; RNR; REN1C; RENIN; REN-1
  • Uniprot ID
    P06281
  • Gene Name
    Ren1; Ren; Ren-1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the pro form of mouse REN1 (NP_112469.1) (Met 1-Arg 402) was fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse REN1 consists of 392 amino acids and has a predicted molecular mass of 43.2 kDa. As a result of glycosylation, the apparent molecular mass of rmREN1 is approximately 48-55 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    1. Measured by its ability to cleave the fluorogenic peptide substrate 5­FAM/QXL™ 520 (Peti­Peterdi, J. et al., 2009, Physiology 24:88.). The specific activity is > 20 pmoles/min/μg.
    2. Immobilized mouse REN1-His (Cat: 502823) at 10ug/ml (100 μl/well) can bind biotinylated human AGT-His (Cat: 501652) with a linear range of 31.25-250 ng/ml.
  • Validations

    Mouse REN1 / Renin-1 Protein (His Tag) SDS-PAGE

    Mouse REN1 / Renin-1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"