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Product Name
Human UBE2F (His Tag) recombinant protein
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Description
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
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Protein name
NEDD8-conjugating enzyme UBE2F
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Protein short names
2510010F15RIK; NCE2; AI851109
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Uniprot ID
Q969M7
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Gene Name
UBE2F; NCE2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human UBE2F isoform 1 (Q969M7-1) (Met 1-Arg 185) was expressed, with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human UBE2F consisting of 201 amino acids and has a calculated molecular mass of 22.9 kDa. It migrates as a 25 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 94 % as determined by SDS-PAGE
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Validations
Human UBE2F Protein (His Tag) SDS-PAGE
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