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  • Mouse Vegfa/Vegf recombinant protein

Mouse Vegfa/Vegf recombinant protein

Cat.#: 519589

Special Price 156.8 USD

Availability: In Stock
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Product Information

  • Product Name
    Mouse Vegfa/Vegf recombinant protein
  • Documents
  • Description
    Mouse Vascular endothelial growth factor (VEGF or VEGF­A), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the PDGF/VEGF growth factor family that is characterized by a cystine knot structure formed by eight conserved cysteine residues. Alternately spliced isoforms of 120, 164 and 188 aa found in mouse. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt­1) and VEGF R2 (Flk­/KDR) on endothelial cells.Although affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity. VEGF is required during embryogenesis to regulate the proliferation, migration, and survival of endothelial cells.It may play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.
  • Protein name
    vascular endothelial growth factor A(Vegfa)
  • Protein short names
    Vegf
  • Uniprot ID
    Q00731-2
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Vegfa/Vegf Ala27-Arg190 is expressed.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Vegfa/Vegf recombinant protein

    Mouse Vegfa/Vegf recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"