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Product Name
Human MICA (His Tag) recombinant protein
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Description
Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
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Protein name
MHC class I polypeptide-related sequence A
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Protein short names
MIC-A; PERB11.1; DAMA-345G11.2; MICA; FLJ60820; FLJ36918; MGC111087; MGC21250
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Uniprot ID
Q29983
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Gene Name
MICA; PERB11.1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human MICA (AAH16929.1) extracellular domain (Met 1-Gln 308) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human MICA consists of 296 amino acids and has a predicted molecular mass of 34 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh MICA is approximately 55-65 kDa due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human MICA Protein (His Tag) SDS-PAGE
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