-
Product Name
Human METAP1 (Fc Tag) recombinant protein
- Documents
-
Description
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.
-
Protein name
Methionine aminopeptidase 1
-
Protein short names
MAP1A; MKIAA0094; METHIONYL AMINOPEPTIDASE 1; DKFZP781C0419; AW047992; 1700029C17RIK; KIAA0094; METAP1; METAP1A
-
Uniprot ID
P53582
-
Gene Name
METAP1; KIAA0094
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the N-terminal domain (Met 1-Phe 272) of human METAP1 (NP_055958.2) was fused with the Fc region of human IgG1 at the N-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human Fc/METAP1 is a disulfide-linked homodimeric protein. The reduced monomer consists of 509 amino acids and has a predicted molecular mass of 57 kDa. As a result of glycosylation, the apparent molecular mass of rh Fc/METAP1 monomer is approximately 60-65 kDa in SDS-PAGE under reducing conditions.
-
Purity
> 85 % as determined by SDS-PAGE
-
Validations
Human METAP1 Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"