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  • Human C4.4A/LYPD3 (His Tag) recombinant protein

Human C4.4A/LYPD3 (His Tag) recombinant protein

Cat.#: 502957

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Product Information

  • Product Name
    Human C4.4A/LYPD3 (His Tag) recombinant protein
  • Documents
  • Description
    Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4 and LYPD3, is a cell membrane protein which contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression
  • Protein name
    LY6/PLAUR domain containing 3
  • Protein short names
    2310061G07RIK; C4.4A; UNQ491/PRO1007; LYPD3
  • Uniprot ID
    O95274
  • Gene Name
    LYPD3; hCG_20277
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human LYPD3 (NP_055215.2) C-terminal segment (Met 1-His 286) was expressed, with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human LYPD3 consists of 267 amino acids and predictes a molecular mass of 28.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhLYPD3 is approximately 45-60 kDa due to glycosylation.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human C4.4A / LYPD3 Protein (His Tag) SDS-PAGE

    Human C4.4A / LYPD3 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"