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  • Human LYPD3/C4.4A/UNQ491/PRO1007 (His tag) recombinant protein

Human LYPD3/C4.4A/UNQ491/PRO1007 (His tag) recombinant protein

Cat.#: 519605

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Product Information

  • Product Name
    Human LYPD3/C4.4A/UNQ491/PRO1007 (His tag) recombinant protein
  • Documents
  • Description
    Ly6/PLAUR domain containing3 (LYPD-3) is a GPI-linked protein. The structure of LYPD-3 is similar to the urokinasetype plasminogen activator receptor (uPAR). LYPD-3 is a 6 -100 kDa molecule with variable cell type-specific N-O-linked glycosylation, mature human LYPD-3 contains two uPAR/Ly6 domains and a Ser/Thr/Pro-rich (STP) region includes a protease sensitive site . The interaction of LYPD-3 with Laminin 1 and 5 on neighboring cells promotes the adhesion, spreading, and migration of tumor cells. LYPD-3 additionally interacts with Galectin-3 and the anterior gradient proteins AG-2 and AG-3. LYPD-3 overexpression in non-small cell lung cancer is predictive of increased mortality.
  • Protein name
    LY6/PLAUR domain containing 3(LYPD3)
  • Protein short names
    C4.4A; UNQ491; PRO1007
  • Uniprot ID
    O95274
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human LYPD3/C4.4A/UNQ491/PRO1007 Leu31-His286 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human LYPD3/C4.4A/UNQ491/PRO1007 (His tag) recombinant protein

    Human LYPD3/C4.4A/UNQ491/PRO1007 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"