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  • LAD1 antibody
  • LAD1 antibody
  • LAD1 antibody

LAD1 antibody

Cat.#: 112267

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Special Price 239.0 USD

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Product Information

  • Product Name
    LAD1 antibody
  • Documents
  • Description
    LAD1 Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells, HeLa cells, mouse skin tissue. Positive IHC detected in human kidney tissue, human brain tissue, human testis tissue. Observed molecular weight by Western-blot: 48kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    LAD antibody; Lad 1 antibody; LAD1 antibody; LadA antibody; ladinin 1 antibody; Linear IgA disease antigen antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of LAD1 recombinant protein (Accession Number: BC009742). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:112267(LAD1 antibody) at dilution of 1:400

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:112267(LAD1 antibody) at dilution of 1:400

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:112267(LAD1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:112267(LAD1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:112267(LAD1 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:112267(LAD1 antibody) at dilution of 1:100 (under 40x lens)

  • Background
    Ladinin-1, also named as LADA, or LAD1, is an anchoring filament protein which is a component of the basement membrane zone. It is a novel component of the basement membranes and may function in contributing to the stability of the association of the epithelial layers with the underlying mesenchyme. Human ladinin is an autoantigen associated with linear IgA disease. It is a secreted protein. Immunohistochemical staining of 16136-1-AP shows strong extracellular matrixc positivity in human testis. The predicted MW of this protein is 57 kDa. Both IP and WB result of 16136-1-AP detected 48 kDa band which may due to post-translation cleavage.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"