-
Product Name
Mouse KIRREL1/NEPH1 (His Tag) recombinant protein
- Documents
-
Description
Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
-
Protein name
Kin of IRRE-like protein 1
-
Protein short names
MGC129543; FLJ10845; 6720469N11RIK; MGC129542; NEPH1; KIRREL; KIRREL1; RP11-444M10.2
-
Uniprot ID
Q80W68
-
Gene Name
Kirrel; Kirrel1; Neph1
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain of mouse KIRREL1 (NP_570937.2) (Met 1-Leu 525) was expressed with a C-terminal polyhistidine tag.
-
Protein Species
Mouse
-
Molecular weight
The secreted recombinant mouse KIRREL1 consists of 489 amino acids and has a calculated molecular mass of 53.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 65-70 kDa protein in SDS-PAGE under reducing conditions.
-
Purity
> 98 % as determined by SDS-PAGE
-
Activity
Measured by the ability of the immobilized protein to support the adhesion of MS1 mouse pancreatic islet endothelial cells (ATCC: CRL2279).
When cells are added to KIRREL1 coated plates (30 μg/mL, 100 μL/well), > 40% cells will adhere specifically after 90 minutes at 37 ℃. -
Validations
Mouse KIRREL1 / NEPH1 Protein (His Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"