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  • Rat IL-1RA/IL1RN (Fc Tag) recombinant protein

Rat IL-1RA/IL1RN (Fc Tag) recombinant protein

Cat.#: 502306

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Product Information

  • Product Name
    Rat IL-1RA/IL1RN (Fc Tag) recombinant protein
  • Documents
  • Description
    Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity (By similarity).
  • Protein name
    Interleukin-1 receptor antagonist protein
  • Protein short names
    IL1F3; MGC10430; ICIL-1RA; IRAP; IL1RN; F630041P17RIK; MVCD4; IL1RA; DIRA; IL-1RN; IL-1RA; IL-1RA3; RP23-218B17.2
  • Uniprot ID
    P25086
  • Gene Name
    Il1rn; Il-1ra
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat IL1RN (P25086) (His27-Gln178) was expressed, fused with Fc region of human IgG1 at the N-terminus.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat IL1RN comprises 412 amino acids and predicts a molecular mass of 45.8 kDa. The apparent molecular mass of the recombinant protein is approximately 47 kDa in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    > 85 % as determined by SDS-PAGE
  • Activity
    Immobilized rat IL1R1-His (Cat:504237) at 10 μg/ml (100 μl/well) can bind rat Fc-IL1RN, The EC50 of rat Fc-IL1RN is 5.1-11.9 ng/ml.
  • Validations

    Rat IL-1RA / IL1RN Protein (Fc Tag) SDS-PAGE

    Rat IL-1RA / IL1RN Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"