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  • Human IL1RN/IL1F3/IL1RA recombinant protein

Human IL1RN/IL1F3/IL1RA recombinant protein

Cat.#: 518864

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Special Price 642.7 USD

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Product Information

  • Product Name
    Human IL1RN/IL1F3/IL1RA recombinant protein
  • Documents
  • Description
    Interleukin-1 Receptor Antagonist (IL-1RN) is a member of the IL-1 family. Endogenous IL-1RN is produced in numerous animal disease models as well as in human autoimmune and chronic inflammatory diseases. It binds to IL-1 receptors in competition with IL-1, but does not elicit intracellular response from this binding. Its role in counteracting the proinflammatory effects of IL-1 is being studied by numerous research groups. IL-4 and IL-13 have been shown to amplify the stimulatory effect of IL1-beta on the production of soluble and intracellular forms of IL-1RN. The regulated expression of IL-1RN in various cell types has been shown to be influenced by cytokines. In synovial fibroblasts, IL-1, TNF-alpha, or PDGF markedly enhances the synthesis of IL-1RN.
  • Protein name
    interleukin 1 receptor antagonist(IL1RN)
  • Protein short names
    IL1F3; IL1RA
  • Uniprot ID
    P18510
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human IL1RN/IL1F3/IL1RA Arg26-Glu177 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human IL1RN/IL1F3/IL1RA recombinant protein

    Human IL1RN/IL1F3/IL1RA recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"