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Sus scrofa (Pig) IL-1 beta (Pig) recombinant protein

Cat.#: 500445

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Product Information

  • Product Name
    Sus scrofa (Pig) IL-1 beta (Pig) recombinant protein
  • Documents
  • Description
    Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Protein name
    Interleukin-1 beta
  • Protein short names
    IL1B; IL1-BETA; IL-1BETA; IL1F2; IL-1 BETA; IL-1; IL-1B
  • Uniprot ID
    P26889
  • Gene Name
    IL1B
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the sus scrofa IL1B (NP_999220.1) (Ala115-Pro267) was expressed with an initial Met.
  • Protein Species
    Sus scrofa (Pig)
  • Molecular weight
    The recombinant sus scrofa IL1B consists 154 amino acids and predicts a molecular mass of 17.7 kDa.
  • Purity
    > 90 % as determined by SDS-PAGE.
  • Activity
    Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons,J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens,M.J. et al. (eds): IRL Press. 272.
    The ED50 for this effect is typically 0.08-0.4 ng/mL.
  • Validations

    IL1B protein SDS-PAGE

    IL1B protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"