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Product Name
Human TIMP1/CLGI/TIMP (His tag) recombinant protein
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Description
Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
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Protein name
TIMP metallopeptidase inhibitor 1(TIMP1)
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Protein short names
CLGI; TIMP
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Uniprot ID
P01033
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human TIMP1/CLGI/TIMP Cys24-Ala207 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human TIMP1/CLGI/TIMP (His tag) recombinant protein
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