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Product Name
Human PI4KB/PIK4CB (His tag) recombinant protein
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Description
Phosphatidylinositol 4-Kinase β (PI4KB) belongs to the PI3/PI4-kinase family and Type III PI4K subfamily. PI4KB contains one PI3K/PI4K domain and one PIK helical domain. It is highly expressed in heart, skeletal muscle, pancreas, testis and ovary,; it is lowly expressed in liver tissue. PI4KB kinase activity can be inhibited by wortmannin, and increased by interacting with NCS1/FREQ. PI4KB phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). In addition, PI4KB may regulate Golgi disintegration/reorganization during mitosis.
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Protein name
phosphatidylinositol 4-kinase beta(PI4KB)
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Protein short names
PIK4CB
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Uniprot ID
Q9UBF8-2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PI4KB/PIK4CB Met1-Met801 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PI4KB/PIK4CB (His tag) recombinant protein
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