Human NCR3/1C7/LY117 (His tag) recombinant protein

Cat.#: 518572

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Product Information

  • Product Name
    Human NCR3/1C7/LY117 (His tag) recombinant protein
  • Documents
  • Description
    Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.
  • Protein name
    natural cytotoxicity triggering receptor 3(NCR3)
  • Protein short names
    1C7; LY117
  • Uniprot ID
    O14931
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human NCR3/1C7/LY117 Leu19-Thr138 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human NCR3/1C7/LY117 (His tag) recombinant protein

    Human NCR3/1C7/LY117 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"