Human CCL15/MIP-5/MIP-1 delta (aa 22-113? His Tag) recombinant protein

Cat.#: 503460

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Product Information

  • Product Name
    Human CCL15/MIP-5/MIP-1 delta (aa 22-113? His Tag) recombinant protein
  • Documents
  • Description
    Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.
  • Protein name
    C-C motif chemokine 15
  • Protein short names
    NCC-3; MRP-2B; HMRP-2B; LKN1; SY15; SCYA15; MIP-5; CCL15; NCC3; MIP-1D; MIP-1 DELTA; LKN-1; HCC-2; SCYL3
  • Uniprot ID
    Q16663
  • Gene Name
    CCL15; MIP5; NCC3; SCYA15
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human CCL15 (Q16663-1) (Gln 22-Ile 113) was expressed, with a polyhistide tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CCL15 consisting of 103 amino acids and has a calculated molecular mass of 11.7 kDa. It migrates as an approximately 13 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human CCL15 / MIP-5 / MIP-1 delta Protein (aa 22-113? His Tag) SDS-PAGE

    Human CCL15 / MIP-5 / MIP-1 delta Protein (aa 22-113? His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"