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Product Name
Human BCAS2/DAM1 (His tag) recombinant protein
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Description
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.
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Protein name
breast carcinoma amplified sequence 2(BCAS2)
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Protein short names
DAM1
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Uniprot ID
O75934
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human BCAS2/DAM1 Ala2-Phe225 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human BCAS2/DAM1 (His tag) recombinant protein
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