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  • HBEGF Polyclonal Antibody

HBEGF Polyclonal Antibody

Cat.#: 163380

Special Price 174.2 USD

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Product Information

  • Product Name
    HBEGF Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to HBEGF
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    HBEGF antibody; DTR antibody; DTS antibody; DTSF antibody; HEGFL antibody; heparin binding EGF like growth factor antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human HBEGF (NP_001936.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - HBEGF Polyclonal Antibody

    Western blot - HBEGF Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using HBEGF antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

  • Background
    Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"