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  • Cytokeratin 14 antibody
  • Cytokeratin 14 antibody
  • Cytokeratin 14 antibody
  • Cytokeratin 14 antibody

Cytokeratin 14 antibody

Cat.#: 109793

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Special Price 239.0 USD

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Product Information

  • Product Name
    Cytokeratin 14 antibody
  • Documents
  • Description
    Cytokeratin 14 Rabbit Polyclonal antibody. Positive IHC detected in human skin tissue, human breast cancer tissue, human cervical cancer tissue, human lung cancer tissue. Positive IP detected in mouse skin tissue. Positive WB detected in mouse skin tissue. Observed molecular weight by Western-blot: 52 kDa
  • Tested applications
    ELISA, WB, IP, IHC
  • Species reactivity
    Human, Mouse, Rat; other species not tested.
  • Alternative names
    CK 14 antibody; CK14 antibody; Cytokeratin 14 antibody; EBS3 antibody; EBS4 antibody; K14 antibody; keratin 14 antibody; KRT14 antibody; NFJ antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Cytokeratin 14 recombinant protein (Accession Number: BC002690). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:500-1:5000

    IHC: 1:50-1:500

  • Validations

    mouse skin tissue were subjected to SDS PAGE followed by western blot with Catalog No:109793(KRT14 antibody) at dilution of 1:1000

    mouse skin tissue were subjected to SDS PAGE followed by western blot with Catalog No:109793(KRT14 antibody) at dilution of 1:1000

    IP Result of anti-KRT14 (IP:Catalog No:109793, 4ug; Detection:Catalog No:109793 1:1000) with mouse skin tissue lysate 3200ug.

    IP Result of anti-KRT14 (IP:Catalog No:109793, 4ug; Detection:Catalog No:109793 1:1000) with mouse skin tissue lysate 3200ug.

    Immunohistochemistry of paraffin-embedded human skin tissue slide using Catalog No:109793(KRT14 Antibody) at dilution of 1:200 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human skin tissue slide using Catalog No:109793(KRT14 Antibody) at dilution of 1:200 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human skin tissue slide using Catalog No:109793(KRT14 Antibody) at dilution of 1:200 (under 40x lens).

    Immunohistochemistry of paraffin-embedded human skin tissue slide using Catalog No:109793(KRT14 Antibody) at dilution of 1:200 (under 40x lens).

  • Background
    Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin 14 is a type I cytokeratin. It is usually found as a heterotetramer with keratin 5. Keratins K14 and K5 have long been considered to be biochemical markers of the stratified squamous epithelia, including epidermis. This antibody is specifically agianst KRT14.
  • References
    • Vijayalingam S, Kuppuswamy M, Subramanian T. Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model. Cancer gene therapy. 21(6):228-37. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"