Cytokeratin 14 antibody

Cytokeratin 14 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Cytokeratin 14 Rabbit Polyclonal antibody. Positive IHC detected in human skin tissue, human breast cancer tissue, human cervical cancer tissue, human lung cancer tissue. Positive IP detected in mouse skin tissue. Positive WB detected in mouse skin tissue. Observed molecular weight by Western-blot: 52 kDa

ELISA, WB, IP, IHC

Human, Mouse, Rat; other species not tested.

CK 14 antibody; CK14 antibody; Cytokeratin 14 antibody; EBS3 antibody; EBS4 antibody; K14 antibody; keratin 14 antibody; KRT14 antibody; NFJ antibody

Rabbit IgG

This antibody was obtained by immunization of Cytokeratin 14 recombinant protein (Accession Number: NM_000526). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin 14 is a type I cytokeratin. It is usually found as a heterotetramer with keratin 5. Keratins K14 and K5 have long been considered to be biochemical markers of the stratified squamous epithelia, including epidermis. This antibody is specifically agianst KRT14.

• Vijayalingam S, Kuppuswamy M, Subramanian T. Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model. Cancer gene therapy. 21(6):228-37. 2014.