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Human Cystatin B / CSTB (His Tag) recombinant protein

Cat.#: 501442

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Product Information

  • Product Name
    Human Cystatin B / CSTB (His Tag) recombinant protein
  • Documents
  • Description
    This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
  • Protein name
    Cystatin-B
  • Uniprot ID
    P04080
  • Gene Name
    CSTB; CST6; STFB
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human CSTB (P04080) (Met 2-Phe 98) was expressed, with a polyhistide tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CSTB consisting of 108 amino acids and has a calculated molecular mass of 12.5 kDa. It migrates as an approximately 15 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate Z-FR-AMC (R&D Systems, Catalog # ES009). The IC50 value is < 15 nM.
  • Validations

    Human Cystatin B / CSTB Protein (His Tag) SDS-PAGE

    Human Cystatin B / CSTB Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"