Cynomolgus REG1A (His Tag) recombinant protein

Cat.#: 504160

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Product Information

  • Product Name
    Cynomolgus REG1A (His Tag) recombinant protein
  • Documents
  • Description
    Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopathy. REG I has been shown to be crucial for induction of ductal epithelial cells to differentiate into some cells. Lithostathine-1-alpha, also known as Pancreatic stone protein, Pancreatic thread protein, Regenerating islet-derived protein 1-alpha, REG1A, REG-1-alpha, and PSPS, is highly expressed in fetal and infant brains. REG1A contains one C-type lectin domain and is a known growth factor affecting pancreatic islet beta cells. REG1A may act as an inhibitor of spontaneous calcium carbonate precipitation. It may also be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. REG1A has been reported to be expressed in human cancers, and it may be positively correlated with patient's prognosis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. High levels of REG1A expression by tumor cells are an independent predictor of a poor prognosis in patients with non-small cell lung cancer (NSCLC).
  • Protein name
    Putative uncharacterized protein
  • Protein short names
    RATLITHOST; P19; PSP; REG; ICRF; LITHOST; REG1; REG1A; PSPS; MGC12447; RATRGPI; PTP; RGPI; RGP1; PSPS1
  • Uniprot ID
    G8F4F8
  • Gene Name
    EGM_20398
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the cynomolgus REG1A (G8F4F8) (Met1-Asn166) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Cynomolgus
  • Molecular weight
    The recombinant cynomolgus REG1A comprises 155 amino acids and has a calculated molecular mass of 177 KDa. The apparent molecular mass of it is approximately 19 and 21 KDa respectively in SDS-PAGE.
  • Purity
    (55.6+42.8) % as determined by SDS-PAGE
  • Validations

    Cynomolgus REG1A / PSPS Protein (His Tag) SDS-PAGE

    Cynomolgus REG1A / PSPS Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"