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Product Name
CAPG antibody
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Description
CAPG Mouse Monoclonal antibody. Positive WB detected in Jurkat cells, HeLa cells, HL-60 cells. Observed molecular weight by Western-blot: 39-40 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
Actin regulatory protein CAP G antibody; AFCP antibody; CAPG antibody; Macrophage capping protein antibody; MCP antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of CAPG recombinant protein (Accession Number: XM_011533122). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107031(CAPG Antibody) at dilution of 1:1000
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Background
CapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. Recently it has been reported that the overexpression of CapG is associated with the progression of lung adenocarcinoma as well as lyphatic invasion status of cholangiocarcinoma, which may be used for prognosis of these tumors.(21908955,22155129)
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"