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Product Name
Anti-WDR5 Rabbit antibody
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Description
WDR5 Rabbit monoclonal antibody
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Tested applications
WB, FC
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Species reactivity
Human, Mouse, Rat
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Alternative names
SWD3; BIG-3; CFAP89 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human WDR5
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
FC: 1/20
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Validations
Western blot detection of WDR5 in K562,C6,3T3,Hela cell lysates using WDR5 Rabbit mAb(1:1000 diluted).Predicted band size:37kDa.Observed band size:37kDa.
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Background
Swiss-Prot Acc.P61964.Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"