Anti-phospho-p53 (Ser6) Rabbit antibody

Anti-phospho-p53 (Ser6) Rabbit antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

phospho-p53 (Ser6) Rabbit monoclonal antibody

WB, IHC-P, IP

Human

Rabbit IgG

Antigen: A synthetic phosphopeptide corresponding to residues surrounding Ser6 of human p53

Monoclonal

50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA

Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]