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  • Anti-Phospho-mTOR (Ser2448) Rabbit antibody
  • Anti-Phospho-mTOR (Ser2448) Rabbit antibody

Anti-Phospho-mTOR (Ser2448) Rabbit antibody

Cat.#: 167001

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-Phospho-mTOR (Ser2448) Rabbit antibody
  • Documents
  • Description
    Phospho-mTOR (Ser2448) Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P
  • Species reactivity
    Human, Mouse, Pig
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthesized peptide derived from human Phospho-mTOR (S2448)
  • Clonality
    Polyclonal antibody
  • Formulation
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage instructions
    Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    1:500~1:1000

    1:50~1:100

  • Validations

    Western blot analysis of Phospho-mTOR (S2448) expression in HEK293 cell lysate.

    Western blot analysis of Phospho-mTOR (S2448) expression in HEK293 cell lysate.

    Immunohistochemical analysis of paraffin-embedded human breast cancer, using Phospho-mTOR (S2448) Antibody.

    Immunohistochemical analysis of paraffin-embedded human breast cancer, using Phospho-mTOR (S2448) Antibody.

  • Background
    Swiss-Prot Acc.P42345.An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
  • References
    • Effect of metformin on human periodontal ligament stem cells cultured with polydopamine-templated hydroxyapatite

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"