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Product Name
Anti-Phospho-mTOR (Ser2448) Rabbit antibody
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Description
Phospho-mTOR (Ser2448) Rabbit polyclonal antibody
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Tested applications
WB, IHC-P
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Species reactivity
Human, Mouse, Pig
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human Phospho-mTOR (S2448)
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:500~1:1000
1:50~1:100
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Validations
Western blot analysis of Phospho-mTOR (S2448) expression in HEK293 cell lysate.
Immunohistochemical analysis of paraffin-embedded human breast cancer, using Phospho-mTOR (S2448) Antibody.
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Background
Swiss-Prot Acc.P42345.An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
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References
- Effect of metformin on human periodontal ligament stem cells cultured with polydopamine-templated hydroxyapatite
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"