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Product Name
Anti-Nrf2 Rabbit antibody
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Description
Nrf2 Rabbit polyclonal antibody
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Tested applications
WB, ICC/IF, FC, IP, ChIP
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Species reactivity
Human
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Alternative names
NRF2; HEBP1; IMDDHH antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Nrf2
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
ICC/IF: 1/50
FC: 1/20
IP: 1/20
ChIP: 1/20
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Validations
Western blot detection of Nrf2 in HepG2 cell lysates using Nrf2 Rabbit pAb(1:1000 diluted).Predicted band size:68KDa.Observed band size:100KDa.
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Background
Swiss-Prot Acc.Q16236.Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress and the regulation of cellular redox conditions. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"