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Product Name
Anti-MMP17 antibody
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Description
Rabbit monoclonal antibody to MMP17
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Tested applications
ICC, IF, IHC-P, WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
MMP-17 antibody; MT4MMP antibody; MTMMP4 antibody; MT4-MMP antibody
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Isotype
IgG
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Preparation
This antigen of this antibody was recombinant protein within human mmp17 aa 1-250.
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Clonality
Monoclonal
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Formulation
Liquid, 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
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Applications
ICC: 1:50
IHC-P: 1:50
WB: 1:500
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Validations
Fig1: ICC staining MMP17 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig2: ICC staining MMP17 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-MMP17 antibody. Counter stained with hematoxylin.
- Background
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References
- Puente X S et al. Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res 56:944-949 (1996).
- Martín-Alonso M et al. Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice. Circ Res 117:e13-26 (2015).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"