Anti-ITPA Rabbit antibody

Cat.#: 168926

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-ITPA Rabbit antibody
  • Documents
  • Description
    ITPA Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P
  • Species reactivity
    Human
  • Alternative names
    My049; ITPase; NTPase; C20orf37; dJ794I6.3; HLC14-06-P antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Inosine triphosphate pyrophosphatase
  • Clonality
    Monoclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    1:1000-1:5000

    1:20-1:50

  • Validations

    Western blot detection of ITPA in Hela cell lysates using ITPA Rabbit mAb(1:1000 diluted).Predicted band size:22kDa.Observed band size:22kDa.

    Western blot detection of ITPA in Hela cell lysates using ITPA Rabbit mAb(1:1000 diluted).Predicted band size:22kDa.Observed band size:22kDa.

  • Background
    Swiss-Prot Acc.Q9BY32.Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"