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  • Anti-IGF1 Receptor Rabbit antibody

Anti-IGF1 Receptor Rabbit antibody

Cat.#: 167919

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Special Price 247.7 USD

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Product Information

  • Product Name
    Anti-IGF1 Receptor Rabbit antibody
  • Documents
  • Description
    IGF1 Receptor Rabbit monoclonal antibody
  • Tested applications
    WB, ICC/IF, FC, IP
  • Species reactivity
    Human
  • Isotype
    IgG
  • Preparation
    Antigen: Recombinant protein of human IGF1 Receptor
  • Clonality
    Monoclonal antibody
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    ICC/IF: 1/20

    FC: 1/50

    IP: 1/20

  • Validations

    Western blot detection of IGF1 Receptor in Hela,A549,MCF-7,U251 cell lysates using IGF1 Receptor Rabbit mAb(1:1000 diluted).Predicted band size:155kDa.Observed band size:95kDa.

    Western blot detection of IGF1 Receptor in Hela,A549,MCF-7,U251 cell lysates using IGF1 Receptor Rabbit mAb(1:1000 diluted).Predicted band size:155kDa.Observed band size:95kDa.

  • Background
    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"