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  • Anti-CD86 Rabbit antibody
  • Anti-CD86 Rabbit antibody
  • Anti-CD86 Rabbit antibody

Anti-CD86 Rabbit antibody

Cat.#: 166707

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-CD86 Rabbit antibody
  • Documents
  • Description
    CD86 Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, IP, FC
  • Species reactivity
    Human, Rat
  • Alternative names
    B70; B7-2; B7.2; LAB72; CD28LG2. antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthesized peptide derived from human CD86
  • Clonality
    Polyclonal antibody
  • Formulation
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000-1/2000

    IHC: 1/50-1/200

    ICC/IF: 1/50-1/200

    IP: 1/50

    FC: 1/50

  • Validations

    Western blot analysis of CD86 expression in Raji cell lysate.

    Western blot analysis of CD86 expression in Raji cell lysate.

    Immunofluorescent analysis of K562 cells, using CD86 Antibody .

    Immunofluorescent analysis of K562 cells, using CD86 Antibody .

    Immunohistochemical analysis of paraffin-embedded human tonsil, using CD86 Antibody .

    Immunohistochemical analysis of paraffin-embedded human tonsil, using CD86 Antibody .

  • Background
    Swiss-Prot Acc.P42081.Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"