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Product Name
Mouse MMP-2 (His Tag) recombinant protein
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Description
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues (By similarity).
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Protein name
72 kDa type IV collagenase
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Protein short names
MMP-II; MONA; GELA; MMP2; CLG4; CLG4A; MMP-2; TBE-1
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Uniprot ID
Q3UG07
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Gene Name
Mmp2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Mmp2 (NP_032636.1) (Met409-Cys622) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Mmp2 consists 273 amino acids and predicts a molecular mass of 30.9 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Mmp2 protein SDS-PAGE
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