This is a specialized computational tool for detecting hydrophobic patches on protein surfaces. Through molecular surface triangulation technology, it can precisely identify hydrophobic regions on protein surfaces. These regions play significant roles in protein function, protein-protein interactions, and drug design.
Key Features
Molecular Surface Triangulation : Creates precise protein molecular surface models
Surface Accessibility Calculation : Determines the accessibility of surface atoms
Hydrophobic Patch Detection : Identifies hydrophobic regions on protein surfaces
Area Calculation : Computes the area of surface regions
A maximum of 10 patches will be displayed
Pymol select statement to display each patch
References
- 1. Lijnzaad P, Berendsen HJ, Argos P. A method for detecting hydrophobic patches on protein surfaces. Proteins. 1996 Oct;26(2):192-203. doi: 10.1002/(SICI)1097-0134(199610)26:2<192::AID-PROT9>3.0.CO;2-I. PMID: 8916227.