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JCO: healthy diet improves the prognosis of colorectal cancer

Introduction A new study by the American Cancer Society shows that patients with colorectal cancer who follow a healthy diet have a lower risk of dying from colorectal cancer and other causes, even those who have improved their diet after diagnosis.


There are more than 1.4 million colorectal cancer (CRC) survivors in the United States. Previous studies have shown that dietary quality has a large impact on disease prognosis, and some pre- and post-diagnostic dietary components are associated with survival in patients with CRC. However, studies evaluating dietary patterns of overall dietary quality and CRC-specific mortality are inconsistent, making it difficult to develop evidence-based recommendations for CRC survivors. For more information, researchers led by Dr. Mark A. Guinter, a postdoctoral fellow at the American Cancer Society, reviewed 2,801 men diagnosed with CRC in the American Cancer Society's Large Prospective Cancer Prevention Study- ii (CPS-II) Nutrition Queue. And female data. They found that patients with pre- and post-diagnosis diets met the American Cancer Society guidelines for nutrition and physical activity in cancer prevention with lower all-cause mortality and CRC-specific mortality.

Compared with the control group, the pre-diagnosis diet group, which was most consistent with the ACS diet recommendation, had a 22% reduction in all-cause mortality and a significant reverse trend in CRC-specific mortality.

The post-diagnostic diet pattern is also significantly associated with the risk of death. Patients with the highest ACS scores had a 65% reduction in CRC mortality and a 38% reduction in all-cause mortality compared with patients with the lowest ACS score. 


They concluded that dietary quality can be a potential way to improve the prognosis of patients with CRC. ”

To date, no single study has evaluated the relationship between pre- and post-diagnosis dietary quality changes and mortality risk in CRC survivors. This study is the first. Dr. Mark A. Guinter said.

Overall, the results of the study demonstrate that the high quality of the diet after diagnosis, even if poorly before, may be associated with a lower risk of death. This undoubtedly gives the clinician another mission. After standardizing and rationalizing the treatment plan for patients, it must take a life habit to help patients change their incompatibility with healthy lifestyles, in order to maximize the prognosis of colorectal cancer.


1. Associations of Pre- and Postdiagnosis Diet Quality With Risk of Mortality Among Men and Women With Colorectal Cancer 

2. Healthy diets linked to better outcomes in colorectal cancer

Souce: NovoPro    2018-10-23